Residual Antigen Might Explain Post-Lyme Complications Description A stable molecule in the cell envelope of Borrelia burgdorferi has been implicated in triggering an ongoing immune response.
Tirofiban as Thrombolysis Adjunct for Patients with Acute Ischemic Stroke Description Patients might have benefited from tirofiban, although these findings require confirmation before clinicians change their practice.
Optimal Management of NSTEMI in Older Adults: A Meta-Analysis Description An invasive management strategy did not improve survival compared with a conservative approach but did lower morbidity risk.
Penicillin Allergy Assessments in Children and Adolescents Description The PEN-FAST score accurately identifies young patients who have true penicillin allergies.
Observations from ID and Beyond: Anal Cancer Screening in HIV: When Guidelines Get Ahead of the Evidence Description Dr. Paul Sax, in HIV and ID Observations: We don't know if anal cancer screening actually prevents cancer.
Managing Complicated Urinary Tract Infections Description Updated IDSA guidelines include a stepwise approach to antibiotic selection, recommendations on switching to oral therapy, and shorter treatment courses.
Trends in Placement of PEG Tubes in Patients with Acute Ischemic Stroke Description In recent years, percutaneous endoscopic gastrostomy has been performed less commonly in these patients.
Patients with Provoked Venous Thromboembolism Plus Other Risk Factors: Extend Anticoagulation? Description In this subset of cases, extended anticoagulation lowered risk for VTE recurrence.
Early Sepsis Treatment — Are We Reaching for the Wrong Antibiotics? Description More than 85% of patients with suspected sepsis were overtreated in emergency departments.
Antibiotic Prophylaxis for Patients with Cirrhosis and Upper Gastrointestinal Bleeding Description High-quality evidence to support this practice is lacking.