NEJM Journal Watch - General Medicine

Mechanical AVR was associated with a survival benefit in patients aged ≤60 years.

The two approaches were comparably effective, but anticholinergic side effects were common in the medication group.

A new consensus statement from the American Academy of Pediatrics offers evidence-based guidance.

Ninety-nine percent of hospital chat messages were nonurgent, which highlights the importance of reassessing current digital communication practices.

Bleeding was associated strongly with cancer diagnoses at the site of bleeding.

Behavioral therapy was as effective as drug therapy, with fewer side effects.

The estimated 8-year incidence of ipsilateral invasive breast cancer was relatively low at 11%.

Two more monoclonal antibodies that are not yet approved by the U.S. FDA show promise.

At 6 months, improvement in symptoms was similar with these two interventions.

In a large observational study, beta-blocker use at discharge was associated with lower mortality risk, primarily in the first year.