NEJM Journal Watch - General Medicine

A randomized trial showed that sepsis alerts, based on the qSOFA score, lowered 90-day inpatient mortality.

A meta-analysis suggests that it does, although evidence to support specific presurgical interventions is weak.

No, according to a randomized trial in the U.K.

A randomized trial failed to replicate positive findings seen with a related drug, citalopram, and showed the same troubling side effects.

Pretreatment with IV calcium prevented hypotension in diltiazem-treated patients with atrial fibrillation and tachycardia.

Yes, based on data from a large patient cohort.

Dalbavancin is a viable alternative as stepdown therapy in treating S. aureus bacteremia.

Neither an expectorant nor a mucous secretion regulator prevented bronchiectasis exacerbations during 1 year.

In a large observational study, women with false-positive results were less likely to return for future screening.

Risk for recurrent kidney stones was lower with SGLT-2 inhibitors than with GLP-1 agonists.