Positive Airway Pressure and OSA: A Matter of Life or Death? Description In an observational study, PAP adherence was associated with lower risk for cardiovascular events and death.
Preventing Gastric Cancer by Eradicating Helicobacter pylori Description A meta-analysis suggests that H. pylori eradication lowers gastric cancer incidence by about 40%.
Psilocybin Improved Depression Among Frontline COVID-19 Care Providers Description Treating patients with trauma-related distress might turn out to be the preferred application for this drug.
Patients with Provoked Venous Thromboembolism Plus Other Risk Factors: Extend Anticoagulation? Description In this subset of cases, extended anticoagulation lowered risk for VTE recurrence.
Pharmacologic Management of Neuropathic Pain Description Updated recommendations based on a meta-analysis from an international group of pain specialists.
Pramipexole as an Adjunct for Treatment-Resistant Depression? Description Nearly half of patients who added pramipexole to their current antidepressant had a response at 12 weeks.
Prevention of Acute Episodic Migraine Description A guideline from the American College of Physicians organizes drug treatment options into 3 tiers.
Percutaneous Cholecystostomy for Acute Cholecystitis: Who Benefits? Description A systematic review of published studies supports a limited role in patients with sepsis.
Platelet-Rich Plasma to Ease Greater Trochanteric Pain? Description This blinded trial of autologous PRP showed no benefit for pain or function.
PREVENT: A New Cardiovascular Risk Calculator Description For most patients, this calculator provides substantially lower risk estimates than the previous American Heart Association calculator.