NEJM Journal Watch - General Medicine

New recommendations in these updated American College of Cardiology/American Heart Association guidelines include selective measurement of cardiac biomarkers.

Updated recommendations based on a meta-analysis from an international group of pain specialists.

Nearly half of patients who added pramipexole to their current antidepressant had a response at 12 weeks.

A guideline from the American College of Physicians organizes drug treatment options into 3 tiers.

In this subset of cases, extended anticoagulation lowered risk for VTE recurrence.

This blinded trial of autologous PRP showed no benefit for pain or function.

For most patients, this calculator provides substantially lower risk estimates than the previous American Heart Association calculator.

Patients with severe obesity had higher risk for revisions during the first year following TKA; however, pain was reduced substantially.

A systematic review of published studies supports a limited role in patients with sepsis.

Neither haloperidol nor ziprasidone had significant effects on cognitive, functional, quality-of-life, or psychological outcomes.