NEJM Journal Watch - General Medicine

The recombinant zoster vaccine was effective among Medicare beneficiaries regardless of prior vaccination status.

COVID-19 or influenza infections were associated with higher risk for lung metastases in cancer survivors.

In patients with low-to-moderate thromboembolic risk, 1-year stroke incidence was lower than the 2% threshold for guideline-recommended anticoagulation.

In patients at high risk for recurrent VTE, reduced-dose anticoagulation provided comparable efficacy and was associated with less bleeding.

In this landmark randomized trial, stenting was associated with fewer nondisabling strokes at 4 years.

Rates of major congenital malformations were similar for both.

In patients with an ICD and plasma potassium ≤4.3 mmol/L, boosting the level to 4.5–5.0 mmol/L reduced the risk for ventricular arrhythmias.

rTMS augmentation of antidepressants might be comparable to medication augmentation and is superior to switching to another single antidepressant.

Diabetic ketoacidosis diagnosis was delayed and duration of DKA was longer in patients with euglycemic DKA.

In two large studies, lamotrigine and levetiracetam had similar risk. It's time to reconsider lamotrigine's warning label.