NEJM Journal Watch - General Medicine

Several organizations have issued a new multisociety guidance statement.

Adults hospitalized for RSV had an 18-fold increased incidence of cardiovascular events during the first 28 days after admission.

The recombinant zoster vaccine was effective among Medicare beneficiaries regardless of prior vaccination status.

COVID-19 or influenza infections were associated with higher risk for lung metastases in cancer survivors.

In patients with low-to-moderate thromboembolic risk, 1-year stroke incidence was lower than the 2% threshold for guideline-recommended anticoagulation.

In patients at high risk for recurrent VTE, reduced-dose anticoagulation provided comparable efficacy and was associated with less bleeding.

In this landmark randomized trial, stenting was associated with fewer nondisabling strokes at 4 years.

Rates of major congenital malformations were similar for both.

In patients with an ICD and plasma potassium ≤4.3 mmol/L, boosting the level to 4.5–5.0 mmol/L reduced the risk for ventricular arrhythmias.

rTMS augmentation of antidepressants might be comparable to medication augmentation and is superior to switching to another single antidepressant.