NEJM Journal Watch - General Medicine

Low-quality evidence suggests a modest benefit.

Both strategies yielded similar postoperative outcomes.

In a randomized trial, patients who stopped their β-blockers were slightly more likely to be hospitalized for cardiovascular reasons.

Not according to a randomized trial of supplemental oxygen for patients with severe resting hypoxemia.

Metered-dose inhalers have carbon footprints that are 20 to 30 times larger than those of dry-powder inhalers.

In 15-year follow-up from a randomized trial, outcomes favored surgery over a nonoperative approach.

Outcomes in a randomized trial favored limited fasciectomy over collagenase injections.

The overall failure rate was 10% — central line–associated bloodstream infections, occlusions, and dislodgement were the main culprits.

Compared with placebo, semaglutide provided some knee pain relief in patients with obesity and OA.

In a large, randomized trial, initiation of a direct oral anticoagulant within 4 days of stroke onset provided comparable outcomes to delayed start.