Antibiotics vs. Appendectomy for Imaging-Confirmed Acute Appendicitis in Adults Description Treatment with antibiotics alone was safe and allowed two thirds of patients to avoid appendectomy within 1 year.
Do Statins Affect Risk for Developing Hepatic Decompensation and Hepatocellular Carcinoma? Description In an observational study, statins were associated with lower risk for these outcomes among patients with chronic liver disease.
The Optimal Intensity of Extended-Duration Anticoagulation After Cancer-Associated VTE Description Low-intensity apixaban was not judged less effective than full-intensity apixaban and resulted in fewer clinically relevant bleeding events.
Do NSAIDs Cause Marginal Ulcers in Patients After Gastrojejunostomy? Description Findings from a large cohort suggest the answer is yes.
Prevention of Acute Episodic Migraine Description A guideline from the American College of Physicians organizes drug treatment options into 3 tiers.
When Does Empirical Treatment Fail for Uncomplicated UTIs? Description Be worried about patients in whom treatment has failed previously.
Bleeding During Anticoagulation for Atrial Fibrillation and Subsequent Malignancy Description Bleeding was associated strongly with cancer diagnoses at the site of bleeding.
Cardiovascular Safety of Long-Term Macrolide Therapy in Patients with Bronchiectasis Description In an observational study, macrolide maintenance therapy was associated with fewer adverse cardiovascular events.
Oral vs. Intramuscular Naltrexone for Patients Hospitalized with Alcohol Use Disorder Description Both forms of naltrexone reduce alcohol use equally well.
Does Preoperative Weight Loss Affect Outcomes After Total Hip Arthroplasty? Description For patients with obesity, outcomes were similar regardless of whether they lost weight before surgery or not.