NEJM Journal Watch - General Medicine

Supplementation with ω-3 fatty acids lowered CV-related morbidity and mortality during 2 years of follow-up.

This study provides more evidence that critically ill patients with acute kidney injury and pH ≤7.2 who received sodium bicarbonate are less likely to require renal replacement therapy.

In a randomized trial, femoral nerve block provided better short-term analgesia with fewer adverse effects.

In this landmark randomized trial, stenting was associated with fewer nondisabling strokes at 4 years.

Weekly semaglutide improved overall cardiovascular outcomes in such patients, whether ejection fraction was preserved or reduced.

In a retrospective study, GLP-1 agonists were associated with slower progression to cirrhosis.

A 14-day monitor detected more atrial fibrillation but did not affect hospitalization rates for stroke or hemorrhage.

Both Cologuard Plus and Shield were approved in 2024.

Among patients with insulin-treated diabetes, hypoglycemia was common but usually asymptomatic.

A trio of trials provide more evidence for the safety and efficacy of SPCs to lower blood pressure.