NEJM Journal Watch - General Medicine

For patients with prior contrast-media reactions, switching to a different contrast agent is recommended over premedication.

In an ambulatory cohort with mild-to-moderate symptoms, advising daily fluid restriction provided no benefit.

Iodinated IV contrast agents need not be avoided in patients with mild-to-moderate renal dysfunction.

Updated AABB guidelines strongly recommend lowering platelet transfusion thresholds even further.

In a population-based study, the incidence of stroke was higher among Down syndrome patients than among controls.

In this meta-analysis, patients were twice as likely to have flares during the 3 months after stopping prophylactic colchicine or NSAIDs.

In a retrospective study, patients receiving direct oral anticoagulants had similar rates of intracranial hemorrhage compared with recipients of low-molecular-weight heparin.

Infection significantly increased the risk for at least 18 months, while vaccination mitigated the risk.

In HIV and ID Observations, Dr. Paul Sax recounts a frustrating experience with an insurance company.

In this large observational study, oxygen therapy was linked to fewer hospitalizations.