NEJM Journal Watch - General Medicine

In this review article, the authors encourage referral after any decompensation event regardless of MELD score.

Dr. Paul Sax tells us why he is optimistic about a “negative” study, in HIV and ID Observations.

Among patients with NPH who responded to temporary CSF draining, shunting improved gait and balance but not cognition or urinary incontinence.

Each central nervous system–active medication prescribed at hospital discharge was associated with incrementally higher 12-month readmission rate and mortality.

In a high-risk, difficult-to-treat population, this targeted therapy was superior to another evidence-based psychotherapy, reinforcing that CBT is the suicide-prevention therapy of choice.

In a randomized trial, the Mediterranean diet compared favorably to traditional IBS-sensitive diets.

Screening was associated with 22 fewer prostate cancer deaths per 10,000 men.

Remibrutinib reduced itch and wheal formation in the trials that led to FDA approval.

Useful for advancing care of the critically ill population, less useful at the individual patient's bedside

A new meta-analysis supports antibiotics in this gray area.