NEJM Journal Watch - General Medicine

Pooled clinical trial data support P2Y12 inhibitors over aspirin as monotherapy after DAPT discontinuation.

GLP-1 agonists were linked to greater risk for neovascular age-related macular degeneration.

A network meta-analysis suggests minimal benefits compared with continuous caloric restriction.

We are one step closer to an easily accessible in-home screening option.

More than 60% of patients discharged from intensive care suffered at least one fall, and ≈25% suffered injurious falls.

In an observational study, symptoms improved or resolved in most patients who were able to discontinue opioid use.

Liver enzyme elevations occurred in 6% of study participants who used CBD.

Adults with sickle cell disease who are hospitalized with acute chest syndrome are at higher risk for transfer to intensive care if the SaO2/FiO2 ratio is <310.

Dr. Paul Sax discusses the ‘resignation' of Dr. Vinay Prasad in HIV and ID Observations.

A meta-analysis suggests that sodium supplementation, along with loop diuretics, confers more clinical benefit than loop diuretics alone; however, questions remain, and the practice likely should be limited to subspecialists with advanced heart