NEJM Journal Watch - General Medicine

Patients with obesity who lost weight before TKA did not have better outcomes.

In a randomized trial, withholding immunosuppression in patients with auto-inflammatory diseases did not lower the likelihood of progression to serious infection.

Ninety-nine percent of hospital chat messages were nonurgent, which highlights the importance of reassessing current digital communication practices.

In an observational study, angiotensin-receptor blockers were associated with fewer deaths and adverse cardiovascular events.

Compared with standard vaccine, high-dose vaccine had no relative effectiveness against influenza and pneumonia hospitalizations combined but did reduce influenza-specific hospitalizations in Denmark by 44%.

New studies suggest significant limitations to the score in symptomatic patients.

In this review article, the authors encourage referral after any decompensation event regardless of MELD score.

Dr. Paul Sax tells us why he is optimistic about a “negative” study, in HIV and ID Observations.

Among patients with NPH who responded to temporary CSF draining, shunting improved gait and balance but not cognition or urinary incontinence.

Each central nervous system–active medication prescribed at hospital discharge was associated with incrementally higher 12-month readmission rate and mortality.