NEJM Journal Watch - General Medicine

In this randomized trial, peripherally inserted central catheters made with novel materials did not have lower failure rates than conventional polyurethane PICCs.

Although the risk is small, medium- and high-dose ICS are associated with serious adverse events.

A program of daily meditation plus yoga improved patient-reported outcomes through 12 weeks.

Even a single dose lowered fracture risk during 10 years of follow-up.

In a randomized trial, use of intra-arterial tenecteplase following thrombectomy was not associated with an improved outcome.

Objective brain injury and associated cognitive impairment were noted as long as 1 year after infection with SARS-CoV-2.

In a clinical trial of patients with post-thrombotic syndrome, stent patency rates were comparable with or without add-on aspirin.

We don't have a clear picture of cause and effect, but MNPs were found in high concentrations in autopsied brains of patients with dementia.

Propranolol reduced resting tremor both with and without a cognitive stressor, but levodopa remains the primary treatment for PD tremor.

In patients at high risk for recurrent VTE, reduced-dose anticoagulation provided comparable efficacy and was associated with less bleeding.