NEJM Journal Watch - General Medicine

Association Between ME/CFS and Cardiovascular Disease

Myalgic encephalomyelitis/chronic fatigue syndrome is associated strongly with adverse CV events.

Simpler Approach to a Low-FODMAP Diet for Patients with Irritable Bowel Syndrome

In two small trials, certain FODMAPs were more likely to cause symptoms, and targeted elimination was effective.

Should Physicians Recommend Driving Restrictions After STEMI?

Older patients probably should limit driving for a brief time following acute ST-segment–elevation myocardial infarction.

Postpartum Blood Pressure Control in Hypertensive Disorders of Pregnancy: Is Lower Better?

More-aggressive BP control was associated with a reduced likelihood of ED visits for hypertension within 6 weeks after delivery.

Automated Blood Pressure Measurement — Without a Clinician in the Room

Long and short protocols of multiple “unattended” office BP measurements correlated with 24-hour ambulatory monitoring.

Does Use of Drug-Coated Devices Improve Outcomes in Chronic Limb-Threatening Ischemia?

No, according to a randomized trial in the U.K.

Does Prior Evidence of Macrolide Allergy Portend Subsequent Fidaxomicin Allergy?

A global database study indicated that a macrolide allergy within the prior year, although rare itself, conferred excess risk for allergy to fidaxomicin.

Are Automated Insulin Delivery Devices Useful for Patients with Type 2 Diabetes?

Glycemic outcomes were significantly better across a range of groups.

To Operate or Not to Operate (on Humeral Shaft Fractures): That Is the Question

This randomized trial showed early functional advantages for surgery over bracing, but long-term results were similar.

Comparing Antipseudomonal Antibiotics for Managing Pseudomonas aeruginosa Bacteremia in the ICU

Use of newer antipseudomonal cephalosporins was associated with lower mortality in high-risk patients with Pseudomonas aeruginosa bacteremia.