NEJM Journal Watch - General Medicine

Hip fractures were 30% more common among older people who were taking gabapentinoids.

Tirzepatide significantly decreased the risk for a composite endpoint of worsening heart failure or cardiovascular death.

PAH is more common in older adults and women and is more lethal in men.

Studies suggest that a longer interval would be reasonable, especially in people at lower risk.

Direct-acting oral anticoagulant monotherapy was superior to dual antithrombotic therapy in a randomized trial.

These findings argue against providing testosterone supplementation for men with age-related declining testosterone levels.

In HIV and ID Observations, Dr. Paul Sax shares what he learned while completing a stint doing inpatient ID consults.

Treating inpatients who had asymptomatic BP elevations was associated with risk for acute kidney injury, myocardial infarction, stroke, or death.

In patients with hip fracture and an elevated troponin level, rapid surgical intervention was associated with lower mortality.

An exploratory analysis of randomized data demonstrates higher mortality and less clear benefit of mAFP use in older patients with STEMI-related cardiogenic shock.