NEJM Journal Watch - General Medicine

The authors have retracted a JAMA Internal Medicine paper due to discrepancies in calculations.

A patient-level meta-analysis suggests benefit from lower mean arterial blood pressure goals.

The Endocrine Society abandoned the concept of vitamin D “sufficiency” and advised against most routine testing.

Should we still be recommending β-blockers for patients at lower risk for subsequent adverse cardiovascular events?

A meta-analysis reaffirms generally better outcomes with therapeutic than with prophylactic anticoagulation — with some exceptions.

People with post-traumatic stress disorder had greater response to sertraline plus brexpiprazole than to sertraline alone.

In patients achieving a median LDL level of 35 mg/dL, neuropsychological testing found no change in cognitive function after 5 years of follow-up.

In a pooled individual patient-level meta-analysis of data from four trials, functional outcomes and mortality improved with endovascular therapy despite increased hemorrhage risks.

Lower chloride levels — and possibly better clinical outcomes — were seen with a balanced solution.

A meta-analysis provides information on the sensitivity and specificity of this finding.