First-Line Therapy for C. difficile Colitis: Does Fecal Microbiota Transplantation Have a Role? Description In a randomized trial in Norway, FMT was noninferior to vancomycin.
Is ABG Necessary to Diagnose Hypercarbic Respiratory Failure? Description Venous blood gases, rather than arterial blood gases, should be used as the initial test when screening for hypercarbic respiratory failure.
Shingles Vaccination Probably Protects Against Heart Disease Description In a large observational study, risk for cardiovascular disease was 25% lower among vaccinated people.
Carpal Tunnel Syndrome and Rheumatoid Arthritis Description About 1 in 8 people with RA received a diagnosis of carpal tunnel syndrome before receiving an RA diagnosis.
Inhaled Steroids and Bronchiectasis: Another Reason to Measure Eosinophils Description Many patients with bronchiectasis receive ICS without any indication; those with eosinophilia might benefit most.
When Diagnosing Thrombotic Thrombocytopenic Purpura, Speed Is Critical Description An assay with turnaround time <1 hour demonstrated excellent sensitivity and negative predictive value.
Adrenalectomy for Mild Autonomous Cortisol Secretion Description After surgery, more than half of patients were able to stop taking antihypertensive medications.
Primary Total Knee Arthroplasty in Patients with Severe Obesity Description Patients with severe obesity had higher risk for revisions during the first year following TKA; however, pain was reduced substantially.
Are Antidepressants Associated with Severe Hyponatremia? Description A large cohort study showed a strong association, especially early after drug initiation.
Does Gradual Titration of Semaglutide Improve Tolerability? Description Slower, individualized dose escalation might improve adherence and decrease side effects.