NEJM Journal Watch - General Medicine

Several organizations have issued a new multisociety guidance statement.

This syndrome and typical Cushing syndrome might overlap clinically more than previously thought.

When used for ≤14 days, midline catheters have fewer major complications than PICCs.

Mucus plugs seen on chest CT in patients without evident symptoms were associated with more-severe disease.

A recent meta-analysis suggests that it is safe and effective for syndrome of inappropriate antidiuretic hormone secretion.

In a randomized trial, surgery appeared to be more effective, but caveats apply.

Dr. Paul Sax discusses the results of the PURPOSE 2 trial, which tested lenacapavir for HIV prevention, in HIV and ID Observations.

In 2024, NEJM Journal Watch covered many studies that are not included in our detailed Year in Review feature but still were important contributions to the inpatient literature. Here are brief synopses of some of those studies.

Several trials published in 2024 support effectiveness and short-term safety of electronic cigarette use for smoking cessation.

An incidental finding of extensive coronary calcium was an independent risk factor for subsequent adverse cardiovascular events.